You wake up at night to pee, but not to poop
The sophisticated, intelligent neurons in your gut that control colon contractions, which push out waste, are also influenced by your body’s circadian rhythm, the internal clock that wakes you when it’s light out and makes you feel sleepy at night, says Pankaj J. Pasricha, MD, director of neurogastroenterology at Johns Hopkins Center for Neurogastroenterology. So most people don’t have the urge to empty their colon in the middle of the night. On the other hand, the bladder, which acts a reservoir for the continuous flow of urine produced in the kidneys, can stretch only up to a certain volume before you gotta go. Normally, you can sleep six to eight hours without having to urinate, but certain medical conditions or drinking too much water before bed can wake you to use the bathroom at night.